University of Toronto Science Rockets Into Space

Dec 1, 2017
Heidi Singer

A University of Toronto scientist will perform real-time blood cell analysis on astronauts to determine how time, space and speed affect the immune system – novel research he hopes will lead to new understanding of how stress and other environmental factors impact our ability to fight disease.

Professor Chen WangProfessor Chen Wang

Dr. Chen Wang, professor in the Faculty of Medicine’s Department of Laboratory Medicine and Pathobiology and a clinician-scientist  at Mount Sinai Hospital, will lead the project, called Immuno Profile, to study the astronauts on the International Space Station over the next five years.  Canadian astronaut David Saint-Jacques, a physician, will be part of the next mission to the Space Station, and will participate in a number of Canadian-made health experiments announced by the Canadian Space Agency.

“It has been documented that spaceflight has significant impacts on the immune system, probably due to microgravity, high G force and stress,” says Wang. “So far, all the tests have been performed on ground with blood samples taken before and after spaceflight. This study will be the first time we’ll be able to see the immunity changes in real-time on the International Space Station.”

Wang will use a novel device that astronauts can operate to take finger-prick blood samples on themselves during their flight missions. They will then beam the results down to him for analysis. 

“We expect to see immune cell and cytokine mediator changes,” says Wang. “We’ll develop a way to identify different types of immune cells and to see if the cells are functioning well or not.”

Immune dysfunction relates to many diseases, including cancers, viral infections, MS, type I diabetes, and even the aging process, he says. A space flight provides a unique environment in which to study immune system stressors: the weightlessness of space can also be used to learn more about the less-understood lymphatic system, which depends on pressure to flow properly. 

“We know that lymphocytes are major components of the immune system, and many cytokine immune mediators regulate the immune system in response to stress and environments,” says Wang. “We hope to develop a new model for how the immune system responds to circadian rhythm, and various stresses.” 

Jun 23 Toronto Head and Neck Imaging Symposium
Symposium | 7:00am–4:00pm
Jun 26 Annual Faculty of Medicine Grant Writing Workshop - 2018
Workshop/Seminar | 9:00am–12:00pm
15 – 17
Too Much Medicine Symposium 2018
Symposium | All day
Sep 28 Multi-disciplinary Gynecologic Oncology Annual Lecture Series (MyGOALS)
Lecture | 7:30am–4:45pm
Sep 28 MyGOALS – Multi-disciplinary Gynecologic Oncology Annual Lecture Series
Lecture | 7:30am–4:45pm
16 – 18
CPD Foundations
Workshop/Seminar | 12:00pm–1:30pm
22 – 25
Wilson Centre Atelier - Qualitative Research: An Introduction
Workshop/Seminar | 8:00am–5:00pm


UofT Medicine
Medical residents with an interest in communications can now take an elective honing their writing skills for…
UofT Medicine
Psychiatric disorders likely have important similarities at a molecular level, even though they have always been co…
UofT Medicine
“That was honestly exhausting, having to qualify my mental illness with strangers who didn’t know me at all.”…

UofTMed Magazine

The Humour issue. Is laughter really the best medicine?

Sign up for your free digital copy.
Back to Top