Special Seminar: p53-based Therapy for Cancer

Professor Sir David Lane is one of the scientists credited with the landmark discovery of cancer gene p53 in 1979. p53, called the "Guardian of the genome" is the most frequently mutated gene in human cancer as more than half of human tumours contain mutations in the gene. Sir David is currently Chief Scientist of Singapore’s Agency for Science, Technology and Research (A*STAR) and also the Chairman of Chugai Pharmbody Research Pte Ltd (CPR) which he helped to attract to Singapore. His laboratory is currently working on peptide and antibody based therapies that target the p53 pathway and on the evolution and function of tumor suppressors.